You should never vacuum rodent droppings in your attic because vacuuming can send contaminated particles into the air

https://s3.us-east-005.backblazeb2.com/my-home-blog/why-you-should-never-vacuum-rodent-droppings-in-your-attic.html

You should never vacuum rodent droppings in your attic because vacuuming can send contaminated particles into the air and raise the risk of exposure to rodent-borne diseases.